May, 2024
Event Details
The Third Coast CFAR hosted a hybrid seminar, “Multiscale Computational Studies Reveal Key Insights Into the Molecular Processes Underlying the HIV-1 Lifecycle,” with Gregory A. Voth, PhD, FRSC, from the University of Chicago. Voth presented advances in computational methodology designed to simulate complex biomolecular systems across multiple lengths and time scales. Examples included:
- Results relevant to the maturation of the HIV-1 virion.
- The HIV-1 capsid assembly.
- The interaction of cofactors and drugs such as Lenacapavir with the capsid.
- The entry of the capsid into the nuclear pore complex on its way to the interior of the infected cell nucleus.
About the Presenter
The University of Chicago
Voth is the Haig P. Papazian Distinguished Service Professor of Chemistry at the University of Chicago. He is also a professor at the James Franck Institute and the Institute for Biophysical Dynamics. Voth is a leader in the development and application of theoretical and computational methods to study problems involving the structure and dynamics of complex condensed phase systems, including proteins, membranes, liquids, and materials.