Ending the HIV Epidemic Scientific Working Group

The Ending the HIV Epidemic Scientific Working Group (EHE SWG) aims to catalyze collaborations that promote the adoption and integration of evidence-based practices, interventions, and policies into routine health care and public health that can help end the HIV epidemic. Drawing on the Third Coast CFAR’s strengths in implementation science and partnership building, the EHE SWG responds to the federal initiative, Ending the HIV Epidemic: A Plan for America (EHE), launched in 2019.

About the EHE Initiative

EHE emphasizes the implementation of existing tools to reduce the number of new HIV diagnoses in the 48 counties that account for half of HIV cases in the U.S. Illinois’ Cook County ranks third on this list, despite a decreasing number of new HIV cases each year and improved prevention efforts. The initiative dedicates federal resources to reduce new HIV diagnoses by 75% by 2025 and 90% by 2030. EHE categorizes existing tools ready for scale up by four pillars: diagnose, treat, prevent, and respond.  

To accomplish EHE goals, the National Institutes of Health (NIH), the Centers for Disease Control and Prevention, and the Health Resources and Services Administration are working together to mobilize an effective response. These federal agencies issued RFAs as part of EHE every year since the launch of the initiative. These funds have bolstered established efforts, particularly Getting to Zero Illinois (GTZ-IL), and positioned the EHE SWG to spur innovative science-practice partnerships to eliminate new HIV cases by 2030.

Third Coast CFAR Support for the EHE SWG

To support the EHE initiative, NIH offers supplemental funds through the CFAR P30 for implementation research led by faculty and community- or health department-based partners. EHE Planning Awards support the development of science-practice partnerships and the aims of the Third Coast CFAR’s EHE SWG. Awardees plan future applications to the NIH and other federal agencies for HIV research, evaluation, or innovative service delivery.

Since the launch of the EHE initiative, NIH has issued 15 EHE Supplement Awards to Third Coast CFAR members. Third Coast CFAR’s Development Core has also invested directly in the initiative by competitively selecting nine teams of EHE SWG members to lead internal EHE Planning Awards. The planning award mechanism pre-positions SWG members to pursue larger EHE grants and supplements within the next one to two years. 

The Third Coast CFAR’s scientific cores provide strong support for awardees as the EHE SWG continues to generate new collaborative projects through engagement with many local constituents.

  • In June 2023, the EHE SWG led a seminar, Limited Interaction Targeted Epidemiology to End the HIV Epidemic, which featured five Chicago-based investigators of the Limited Interaction Targeted Epidemiology (LITE) cohort studies from Northwestern University, Lurie Children’s, and the CORE Center. The event was moderated by Jorge Cestou, PhD, MBA, at the Chicago Department of Public Health. Gerald Sharp, DrPH, epidemiologist at the National Institute of Allergy and Infectious Diseases (NIAID), discussed the request for applications for Limited Interaction Targeted Epidemiology: Viral Suppression (LITE-VS). The seminar, which included over 60 attendees, was designed to showcase opportunities for synergy between EHE, Getting to Zero Illinois, CDPH, and LITE grantees.
  • In July 2021, the EHE SWG led a workshop, Developing Community-Academic Research Partnerships, in conjunction with the Third Coast CFAR’s Community Collaboration Board and scientific cores. Three teams presented practical tips on exploring, forming, and expanding partnerships supported by Third Coast CFAR awards and services. 

*Projects may address multiple pillars



Inger Burnett-Zeigler, PhD, Northwestern University
EHE SWG Co-Director

Gregory L. Phillips II, PhD, MS
Northwestern University
EHE SWG Co-Director

Ending the HIV Epidemic Awards Granted in Fiscal Years 2019-23. Types of Awards are 15 NIH Supplements and 9 SWG Planning with 24 Total. Since the launch of the EHE initiative, NIH has issued 15 EHE Supplement Awards to Third Coast CFAR members. CFAR also also selected 9 teams for internal EHE SWG Planning Awards, which can lead to larger EHE grants and supplements. Awards by EHE Initiative Pillars include 16 Prevent, 13 Treat, 6 Diagnose and 2 Respond. Hot Topics in HIV Research Studied include Tailored PrEP Campaigns, Intersectionality and Stigma, Innovative Service Delivery, Service Navigation, Status Neutral Approaches, and Structural Inveterventions.