The Third Coast Center for AIDS Research will co-sponsor a seminar in Northwestern University’s Lectures in Life Sciences series
Wesley I. Sundquist, PhD
Distinguished Professor and Co-Chair
Department of Biochemistry
University of Utah
Cellular, molecular and structural biology of HIV
Lurie Medical Research Center
303 E. Superior Street
Wesley Sundquist, PhD is Samuels Professor and Co-Chair of the Department of Biochemistry at the University of Utah. He is also a member of the Cell Response and Regulation Program at Huntsman Cancer Institute.
Dr. Sundquist’s lab studies the cellular, molecular and structural biology of retroviruses, particularly HIV, and the roles of the ESCRT pathway in cell division and the abscission checkpoint. Major projects in our lab include studies of: 1) ESCRT pathway functions and regulation in cell division, 2) HIV budding, 3) HIV capsid structure, function and restriction, particularly by the TRIM5α system, and 4) Designed enveloped protein nanoparticles. Our approaches include NMR, EM, crystallographic and computational studies of viral complexes, identification and biochemical analyses of the interactions between viral components and their cellular partners, and genetic analyses of viral and cellular protein functions.