March, 2022

202214mar12:00 pm1:00 pmExploring Small Molecule Regulators of the Super Elongation Complex as Novel HIV Latency Reversal AgentsSeminar with Judd Hultquist, PhD and Shimaa Soliman, PhD

Event Details

Monday, March 14, 2022
12–1 p.m.
RSVP on Zoom required.

Judd Hultquist, PhD
Assistant Professor of Medicine
Division of Infectious Diseases
Northwestern University

Shimaa Soliman, PhD
Postdoctoral Fellow, Shiltaifard Lab
Biochemistry and Molecular Genetics
Northwestern University

 

 

 

 

 

 

 

 

 

 

 

Judd Hultquist, PhD is an assistant professor of medicine in the Division of Infectious Diseases and associate director of the Center for Pathogen Genomics and Microbial Evolution in the Institute for Global Health at Northwestern University Feinberg School of Medicine. His laboratory specializes in the development and adaptation of high-throughput, quantitative, systems-based approaches for use in primary models of disease to better understand the host-pathogen relationship. Leveraging diverse expertise in primary cell models, proteomic profiling, and functional genomics, his team works at the intersection of systems biology and infectious disease, defining host-pathogen interactions and their consequences for replication and pathogenesis. Through these efforts, he ultimately hopes to strengthen the bridge from big data to targeted discovery to clinical application for the development of personalized, host-driven therapies and the advancement of human health.

Shimaa Soliman, PhD is a post-doctoral fellow in Ali Shilatifard lab at the department of Biochemistry and Molecular Genetics at Northwestern University Feinberg School of Medicine. Her research focuses on understanding the epigenetic mechanisms governing transcriptional elongation and promoter proximal pause-release. Moreover, she develops small molecular inhibitors targeting transcription elongation complexes that are key regulators of gene expression and their applications as a therapeutic approach to improve the efficacy of current treatments such as HIV latency reversal agents.  The goal of her research is to uncover the epigenetic mechanisms driving certain diseases including cancer and target those pathways to improve patient response to current treatments.

Time

March 14, 2022 12:00 pm - 1:00 pm(GMT+00:00)