Viral Pathogenesis Core

Leadership

Thomas J. Hope, Ph.D.
Northwestern University
Viral Pathogenesis Core Director

 

Internal Advisory Committee
Patrick Kiser, Ph.D.
Northwestern University

Curt Horvath, Ph.D.
Northwestern University

Eva Gottwein, Ph.D.
Northwestern University

Melody Swartz, Ph.D.
The University of Chicago

Scientific Agenda

The Viral Pathogenesis (VP) Core seeks to make the tools of modern biological HIV research accessible to the Third Coast CFAR team to facilitate collaborations between biomedical and behavioral researchers, particularly new researchers.

Services and Resources

Virology Methods and Assays

The Viral Pathogenesis Core facilitates leverages resources to provide cost-efficient, fee-for-service assays and methods of virology including virus quantification by ELISA and PCR.

Genomic Services

Members may access up-to-date next generation sequencing platforms and analyses to facilitate translational HIV research.

Laboratory Infrastructure and Viral Stock

Access to a variety of virology infrastructure and lab needs are available from the VP Core, including the BLS2+ facility, associated training, a characterized viral stock bank, and cell and tissue banks.

Virology Consultation

The VP Core offers a consultation service designed to provide insight and expertise in the design of biological experiments and choice of assays, including recommendations on a choice of reagents including cell lines, virus isolates, assays for quantification, and conditions of the experiment. Consultants will direct members to the appropriate use of the aforementioned laboratory infrastructure and banks.

Training in World Class Imaging Facilities

The VP Core’s imaging facility is a mecca for international researchers seeking training in four Delta vision deconvolution microscope systems, OMX structured illumination-based (SIM) super resolution system, a general use fluorescence microscope with three cameras and microinjection capabilities, all of which are available to Third Coast CFAR members.

Viral Pathogenesis Research Seminars

The VP Core will sponsor several research seminars and participate in the Innovation Program, under the Administrative Core. Research sessions will be embedded in HIV Research Updates and the HIV Lunch and Learn Series. Read more on the Events page.